The anime centers around the titular Ekoda, who works various jobs, and explores the city nightlife. While she has a boyfriend, she is more into casual relationships than taking it seriously. She considers popular girls (which she labels "birds of prey") her natural enemy.
After growing up in Tokyo, high school student Jin Kaito moves to Nagoya where he meets Yatogame Monaka, a fellow student who puts her Nagoya dialect on full display. With her cat-like appearance and unvarnished Nagoya dialect, Yatogame won't open up to him at all. This popular local comedy is increasing the status of Nagoya through observation of the adorable Yatogame-chan!