As long as hearts exist inside people, there will always be those who suffer. And then something "strange" enters their mind and causes a strange disease to manifest itself in the body. The illness, which is called a "mystery disease" is unknown to most, but certainly exists. There is a doctor and apprentice who fights the disease, which modern medicine cannot cure.
His name is Ramune.
He acts freely all the time, is foul-mouthed, and doesn’t even look like a doctor! However, once he is confronted with the mysterious disease, he is able to quickly uncover the root cause of his patients' deep-seated distress and cure them.
And beyond that...
Since the graduation of the senior members of the club, Takezou ends up being the sole member of the "Koto" (traditional Japanese string instrument) club. Now that the new school year has begun, Takezou will have to seek out new members into the club, or the club will become terminated. Out of nowhere, a new member barges into the near-abandoned club room, demanding to join the club. How will Takezou be able to keep his club alive and deal with this rascal of a new member?